The FIFA 4-2-2-2 is among the a lot more common systems used on-line, given its fluidity and difficulty to mark up against. The two defensive midfielders only will need to worry about defending, enabling the two inverted wide guys to drift inside and look to strike at purpose.

FIFA Expert's recommended work rates and player instructions:
Right Back – Medium Attacking / High Defensive
Left Back – Medium Attacking / High Defensive
Right CB – Low Attacking / High Defensive
Left CB – Low Attacking / High Defensive
Right CDM – Low Attacking / High Defensive
Left CDM – Low Attacking / High Defensive
Right CAM – High Attacking / Low Defensive
Left CAM – High Attacking / Low Defensive
Right Striker – Medium Attacking / Low Defensive
Left Striker - High Attacking / Low Defensive

FIFA Expert's recommended (4-2-2-2) player instructions:
Right Back – Balanced attack, Normal interceptions.
Left Back – Balanced attack, Normal interceptions.
Right CB – Stay Back, Normal interceptions.
Left CB – Stay Back, Normal interceptions.
Right CDM – Balanced defence, stay back while attacking.
Left CDM – Balanced defence, stay back while attacking.
Right CAM – Stay forward, get into box for cross, stick to position.
Left CAM – Stay forward, get into box for cross, stick to position.
Right Striker – Basic defence support, stay central, get in behind.
Left Striker - Basic defence support, stay central, get in behind

Strengths: A huge variety of attacking options with, in effect, a front 4. A very balanced formation and you'll always find that you have good numbers of players when defending or attacking. This obviously leads to you having lots of viable options when attacking. The 2 CDM's provide great cover and with 2 hard working full-backs you're going to be defending with 6 players (plus your GK) which will make you extremely hard to break down.

Weaknesses: The 2 CAM's will tend to be positioned in wider areas where they more often than not are not suited. They favour central areas which can leave a lack of wide options. Couple this problem with 2 low attacking work rate full-backs and you're really going to struggle getting any wide play going. If you're someone who likes to cross the ball in lots then I would suggest avoiding this formation. Another potential problem will be getting caught shot defensively, this is a huge problem if you have CDM's with high attacking work rates and can lead to a cluster of players in the CAM position which is obviously easier to defend against.

Key player/position: The 2 CDM's. You can break this formation down into three sections. A front 4, a back 4 and 2 holding midfield men. Obviously the 2 are down on numbers so it is pivotal that you have 2 strong players in that area of the pitch.

Most suited style of play: Medium to fast build-up play. Longer passes to get the ball into the front 4 as quick as possible as there are a lack of numbers in central areas.