If you are searching to minimize the effect in the opponent's creative players, go for the 4-4-3 defend. Your one standard midfielder may have his perform cut out, but if he does obtain the ball in space, appear to release your wide players. The pace on the flanks is vital provided the lack of creativity in the technique. Your full-backs may have a compact attacking part so be sure you prioritize Defence when generating your team choice.

FIFA Expert's 4-3-3 (Holding) recommended work rates:
Right Back – Medium Attacking / High Defensive
Left Back – Medium Attacking / High Defensive
Right CB – Low Attacking / High Defensive
Left CB – Low Attacking / High Defensive
Right CDM – Low Attacking / Medium Defensive
Left CDM – Low Attacking / Medium Defensive
CM – High Attacking / Medium Defensive
Right-Wing – High Attacking / Medium Defensive
Left-Wing – High Attacking / Low Defensive
Striker - High Attacking / Low Defensive

FIFA Expert's recommended (4-3-3 Defence) player instructions:
Right Back – Balanced attack, Normal interceptions.
Left Back – Balanced attack, Normal interceptions.
Right CB – Balanced attack, Normal interceptions.
Left CB – Balanced attack, Normal interceptions.
Right CDM – Cut passing lanes, Stay back while attacking, Normal interceptions.
Left CDM – Cut passing lanes, Stay back while attacking, Normal interceptions.
CM – Get forward, Balanced crossing runs, Normal interceptions, free form.
Right Winger – Stay forward, stay wide, get in behind, get into the box for the cross.
Left Winger – Stay forward, stay wide, get in behind, get into the box for the cross.
Striker – Basic Defence support, Stay central, Get in behind.

Strengths: The 4-3-3 (3) is our one of our favorite version of the various 4-3-3's you can choose as a default set-up (although they are all very similar). The 4-3-3's are one of the most famous formations, and this is understandable for a few reasons. It allows you to mix up your passing style with short passing in the middle as well as the option to hit the wings with more extended passing. The two wingers provide plenty of widths so crossing opportunities will be plentiful and a big reason for its popularity - it's an excellent formation for counter-attacking. The two CDM's provide great cover. 

Weaknesses: The main weakness is that the lone ST can be left exposed when going forward, especially if your wingers lack pace or have medium/high defensive work rates. The weakness of the 4-3-3 with three CM's is eradicated by the CDM's, especially if they have high defensive work rates. 

Key player/position: Your two wingers. In this set-up, it is vital that you choose your wide men wisely. They need to have pace, be comfortable on the ball, excellent dribbling and crossing stats as well as able to score a goal. Having wingers whose healthy foot is on the opposite side is advisable to give you the option to go both ways. E.g. Hazard, right-footed, LW. Choose these players wisely and build your team around them.

Most suited style of play: Wide areas are a crucial part of the success criteria for this formation. Again, focus play initially through the central areas before distributing to wider players. Also suits a counter-attacking style of play