PoE Orb of Alchemy is a Poe currency item that could be utilized to upgrade a piece of standard gear to uncommon. Used to transmute a Typical quality item into a rare, high-quality item. I suggest only getting gear for this Orb while leveling, and later on, use them to create mid and higher tier different maps. Is usually also utilized to improve good quality of sturdy boxes in greater level regions.

Tips on how to Use Orb of Alchemy

Orbs of Alchemy can make use of to upgrade a regular item into a different Item. The resulting uncommon has randomly chosen affixes and has a random number of affixes (ranging from four to six [three to 4 if applied on jewels]). Prevalent use circumstances involve upgrading great regular items (particularly those with suitably linked sockets) during the questing phase of a character's improvement, upgrading a proper map to make the most of the large item quantity bonus from obtaining up to six affixes, and upgrading strongboxes. Orbs of Alchemy are hardly ever applied in the crafting of rare high-end items due to the fact it is less stressful to start with a high magic item and instead use a Regal Orb to upgrade it to an uncommon.
Orbs of Alchemy can also be made use of to buy various items from vendors, which includes maps, skill gems, and unidentified rare Items.
Also, Orbs of Alchemy are also helpful for any quite significant number of crafting bench recipes associated using the Forsaken masters Haku, Elreon, Tora, Catarina, Leo, and Vagan.

How you can Get Orb of Alchemy

Orbs of Alchemy are different currency items that may be dropped by slain monsters, chests, and destructible containers. They also fall from Arcanist's Strongboxes.
Orbs of Alchemy also can be obtained by combining 20 Alchemy Shards, that is in turn acquired by promoting identified magic and different items with specific modifiers to any vendor.
An Orb of Alchemy may be bought from Clarissa in exchange for 1 Orb of Regret. Vagan will sell ten Orbs of Alchemy in exchange for eight Orbs of Regret once every day.
Orbs of Alchemy can also be obtained in the following vendor recipes:

Result	Recipes
1× Orb of AlchemyOrb of AlchemyStack Size: 10Upgrades a normal item to a rare itemRight click this item then left click a normal item to apply it. Shift click to unstack.	3 x Identified rare items with the same name
1× Orb of AlchemyOrb of AlchemyStack Size: 10Upgrades a normal item to a rare itemRight click this item then left click a normal item to apply it. Shift click to unstack.	2 x Identified rare items with same name and both 20% quality
1× Orb of AlchemyOrb of AlchemyStack Size: 10Upgrades a normal item to a rare itemRight click this item then left click a normal item to apply it. Shift click to unstack.	1 x normal, 1 x magic, 1 x rare (all 20% quality) of the same base type
2× Orb of AlchemyOrb of AlchemyStack Size: 10Upgrades a normal item to a rare itemRight click this item then left click a normal item to apply it. Shift click to unstack.	1 x normal, 1 x magic, 1 x rare (all 20% quality and unidentified) of the same base type

You can sell any white (non-magical) weapon, a blacksmith's whetstone and a rustic sash for the vendor to get an Increased Physical Damage weapon with the same sort. The amount of damage is dependent around the rarity from the sash. So I use alchemy orbs on the sashes, do that recipe, and get back a reliable 70-80% IPD weapon. Then use Orbs of augmentation to see what suffix it gets.

It's not the sort of issue players with a lot of wealth will do, but for self-found and races, it may be beneficial.

Get a headache just wanting to figure out this vendor nonsense. Always up for a challenge but considering that we all get a boatload of great socketed linked white items the experimentation system fails entirely with the inability to craft a decent quantity of Alchs to work with. We all have boatloads of Orbs of Wisdom. However, the tedious method to get to an Alch is just crazy stupid.
Come on devs please give us an improved (more straightforward) way to craft some Alchs.
Presently have +22% IIQ and +17% IIR + a +40% item rarity help gem on my poison arrow attack.
Read a post of an individual acquiring +92%IIQ to complete farming runs so can do superior with extra time and luck to have greater gear however the existing strategy to craft an Alch is just not worth the work.

Divination cards
A set of 5 Emperor's Luck is usually exchanged for 5 Orbs of Alchemy.
A set of 3 The Survivalist may be exchanged for seven Orbs of Alchemy.